Chronic alcohol consumption and intestinal thiamin absorption: effects on physiological and molecular parameters of the uptake process
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TRANSLATIONAL PHYSIOLOGY Chronic alcohol consumption and intestinal thiamin absorption: effects on physiological and molecular parameters of the uptake process
Subramanya SB, Subramanian VS, Said HM. Chronic alcohol consumption and intestinal thiamin absorption: effects on physiological and molecular parameters of the uptake process. Am J Physiol Gastrointest Liver Physiol 299: G23–G31, 2010. First published May 6, 2010; doi:10.1152/ajpgi.00132.2010.—Thiamin is essential for normal cellular functions, and its deficiency leads to a variety of clinical ...
متن کاملChronic alcohol consumption and intestinal thiamin absorption: effects on physiological and molecular parameters of the uptake process.
Thiamin is essential for normal cellular functions, and its deficiency leads to a variety of clinical abnormalities. Humans and other mammals obtain the vitamin via intestinal absorption. The intestine is exposed to two sources of thiamin, a dietary and a bacterial (i.e., normal microflora of the large intestine) source. Chronic alcohol consumption is associated with thiamin deficiency, which i...
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The renal thiamin reabsorption process plays an important role in regulating thiamin body homeostasis and involves both thiamin transporters-1 and -2 (THTR1 and THTR2). Chronic alcohol use is associated with thiamin deficiency. Although a variety of factors contribute to the development of this deficiency, effects of chronic alcohol use on renal thiamin transport have not been thoroughly examin...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Gastrointestinal and Liver Physiology
سال: 2010
ISSN: 0193-1857,1522-1547
DOI: 10.1152/ajpgi.00132.2010